Yep! a dozen of them.
Started with the SRAM etap HRD first gen 11sp, with a 40T garbaruk ring and a 11/36 cassette.
Then with AXS Red and Force shifters, with Rival ones at the end of this month.
And AXS Eagle XX1, X01 and now GX derailleurs.
Usually with a 46T ring round or 44 oval and 10/50 or 10/52 cassettes.
Even one with an AXS Reverb, hitting both shifter pads to trigger it.
A friend went with a mechanical 12sp Eagle derailleur and the Gevenalle lever.
But in this case you need to check where the shifter cable exit the frame.
Road/Gravel bikers have the cable exit at the very end of the seatstay/chainstay.
While an MTB derailleur is designed for a cable exit below the chainstay, forcing you to an unusual hose path to the derailleur.
Here is a good set of options:
https://bikepacking.com/gear/guide-to-mullet-drivetrains/