IMHO there's more than just one answer to that question.
In a world where all of the framests are true to the standards: Something like BB30 where the bearings are directly pressed into the frame wins.
In a world where there's only little variability on the frames: Pressfit with cup like bb86 or bb386 will be best choice for beeing lighter etc (see all the other things above)
From a maintenance point: Threaded BBs are so much nicer to work with, especially if your customers don't care about there stuff at all until it's way too late.
For all of the points: Bigger bearings will be more reliable since the balls can be bigger.
Especially the last point makes BB86 one of the worst systems imho. Having too many people around racing on 30mm spindles in a 41mm shell. The BBs just can't hold up as long.
If I'd have the choice - I'd go for BB386 anytime - you've got the plastic cups to mitigate bad QC, you'll have more reliabilty than with BB86, you wont have the threads and all the potential problems with debonding, seizing, etc.
As for flex - I believe that you probably feel more flex from the frame around the BB-Area. Where the Down-tube meets the BB-Shell. They'll call it "engineered compliance" and ask a premium for it soon
