I was reading that tubeless sealant might contaminate the pure nitrogen, so you won't really benefit from the longevity it'll provide from pressure loss. There's also the possibility the sealant won't react properly sealing punctures since there's less oxygen in the tires. Though I'm no chemist, so for all I know everything I read was just BS and it'll work great!
Though if you can get free nitrogen at Costco and the container only cost like $35 USD, I'd get it as a cheap way to have pressurized gas for beading tires. I'm too cheap to get a compressor so I usually just bead my tires at the gas station pump.
Omg "tubeless sealant might contaminate the pure nitrogen thats rich"... the air we breathe is 78% nitrogen.
as for "There's also the possibility the sealant won't react properly sealing punctures since there's less oxygen in the tires." That sounds more likely but there is the outside o2 that causes hardening. Sealant actually has lil fibers that form the structure of the patch. and then hardens.
One way to fix this is "set" your seatant with normal o2 and then after a ride of 2 switch to nitrogen... Because then its already ready. but then it does then leak out the tire... so who knows.. I would think if you set it it would be fine... but I wouldn't do it.... maybe if I was top athlete in the world trying for any edge... but day to day riding its silly.