I have built 4 velobuild frames with sensah mechanical. it works. It's a MAJOR pain, but it works. Front derailleurs tend to be the worst performers. You kind of NEED to buy brake cables that are road specific. that way the other end is smooth and slides in housing despite the shitty angles. if you have cables that you snip on one end, unless you're a soldering maestro, the end of the wire catches in sharp angles in the housing and after a while you want to burn society to the ground and go live in the woods.
I havent ridden more than c.450km on my ltwoo er9, but so far i LOVE it. it means 2 cables instead of 4 to route via the headset area, which makes it a breeze in comparison. The geekiest may be mechanical at the back, and electronic at the front. that would a frankenbuild though. 3 cables much better than 4 still. You could do mechanical disc and mechanical shift at the rear, and hydraulic and electronic at the front. You would woo the ladies with your engineering acumen. They'd be like "please take me here now". Maybe.